Buy ARA-290 Peptide
Order ARA-290, a nonerythropoietic erythropoietin-derived peptide that is aimed at combating inflammation and promoting the repair of nerves without serious side effects.
Check out our entire range of ARA-290 peptides
Order ARA-290, a nonerythropoietic erythropoietin-derived peptide that is aimed at combating inflammation and promoting the repair of nerves without serious side effects.
Check out our entire range of ARA-290 peptides
ARA-290 is a small molecule peptide and is based on erythropoietin, which is a protein involved in the production of red blood cells. ARA-290 appears to not increase red blood cell production, unlike the erythropoietin hormone. It functions mainly through interaction with certain receptors, i.e., the innate repair receptor (IRR). It has anti-inflammatory properties and aids in tissue repair.
Research indicates that the peptide could be useful in treating autoimmune diseases, chronic pain, and diabetic neuropathy. Its anti-inflammatory effect in nerves and promoting healing, I believe makes it a good candidate for further medical research.
It functions through activation of the intrinsic repair receptor (IRR). The receptor complex IRR is composed of a beta common receptor and an erythropoietin receptor that are present on the surface of some cells.
This receptor is turned on when it becomes activated and sets into motion protective pathways in the body. Research has proven it decreases inflammation and helps damaged tissues heal. By stopping the pro-inflammatory signals, it is able to avoid additional tissue damage. It also shall promote cell survival and regeneration. https://direct-peptides.com/ara-290-category/
ARA-290 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain in Rats By Exploiting the Anti-Inflammatory and Neuroprotective Effects of Erythropoietin. Unlike the traditional erythropoietin, which promotes production of red blood cells and can have side effects. This directed action makes Nervive less toxic and more effective for prolonged use against nerve-related conditions,damaged nerves, and chronic pain.
Sequence: H-Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH
Molecular Formula: C51H84N16O21
Molecular Weight: 1257.3 g/mol
PubChem CID: 91810664
Neuropathic Symptoms: The 11 amino acid erythropoietin derivitive has been shown to decrease neuropathic symptoms in persons with type 2 diabetes and sarcoidosis. It can be administered by either IV (intravenous) or subcutaneous routes in the form of injections, thereby being a versatile therapeutic option.
Metabolic control: In addition to neuropathic symptoms, it also demonstrates favorable impacts either on metabolic control in patients with type 2 diabetes. This bimodal activity profile may render it a promising treatment for complex, co-morbid disorder[s]."
Elevates Corneal Nerve Fiber Density: It was shown to elevate corneal nerve fiber density in patients with sarcoidosis-related small nerve fiber loss. This indicates its regenerative ability through action on the innate repair receptor.
Treatment of Chronic Neuropathic Pain: It is a ligand for the innate repair receptor, which consists of the erythropoietin and β-common receptors as a heteromer. It is this mode of action which has been postulated for the relief of chronic neuropathic pain in sarcoidosis.
SPECT Tracer for Cardiac Ischemia: It has been investigated as an agent for Single Photon Emission Computed Tomography (SPECT) imaging of ischemic areas in the heart. There are diagnostic implications to this finding.
Neuropathic Pain: Painful Diabetic Neuropathy Clinical studies have demonstrated safety and efficacy of the peptide on treating painful diabetic neuropathy [6]. Additional larger clinical trials are required for more definitive results.
Potential neuroprotective effects Besides its analgesic activity, it also seems to have neuroprotective potential so that it could be used for post-stroke depression.
Anti-Apoptosis and Anti-Inflammation: It has been investigated for its anti-apoptotic and anti-inflammatory action in critical limb ischemia, indicating that it may be used to treat vascular diseases.
Cytokine-Induced Apoptosis Inhibition: It has been shown that it protects rat islets from cytokine-induced apoptosis [8] and may potentially be used in autoimmune disorders.
Tissue Damage: Studies suggest it can help in the reduction of tissue damage as it reduces inflammation.
Immune System Improvement: it appears useful for its ability to stimulate the immune system through the inhibition of the TPR pathway, and thereby potential decrease in immflamatory cells such as IL-6, and aid those with depressed immunity. It is also showed that it may act on adaptive immunity, through the modification of antigen presentation by dendritic cells, and thereby improve outcome in transplantation models.
Purchase ARA-290 peptide vial 2 mg, a lyophilized powder for laboratory research. As a synthetic erythropoietin mimetic, it stimulates the innate repair receptor while not affecting red blood cell production. Find it here at Direct Peptides, and trust us it's perfect for researching both inflammation and Tissue repair therapies.
Purchase ARA-290 Nasal Spray, 15ml and 30 ml bottles The nasal spray can be made in a variety of sizes, for short to longer term studies. The 15 ml size is perfect for experimenting, and the 30 ml economy size even more so. The same high-quality formula delivered in an easy-to-use nasal spray 2 sizes to choose from.
What is ARA-290?
It's a synthetic peptide agent inspired from erythropoietin to exploit therapeutic effects without the erythropoietic effects. It has also been studied for its anti-inflammatory, analgesic and neuroprotective activities.
What are they studying ARA-290 for?
It is under investigation as a possible treatment for neuropathic pain, critical limb ischemia, autoimmune diseases and post-stroke depression. Attention has been focused on its ability for tissue preservation and inflammation modulation.
How does ARA-290 work?
Its mechanism of action seems to be mediated by the Innnate repair receptor, a mediator associated with tissue protection and repair. By bonding this receptor, it may play a role in decreasing inflammation, apoptosis and pain.
ARA-290 Is ARA-290 approved for and specific medical use?
It is currently still in the process of clinical trials, and has not yet been widely approved for medical use by the U.S. Food & Drug Administration (FDA). The potential that has been shown in these trials is promising, but still needs to be validated through FDA regulated clinical trials.
Are there risks to ARA-290?
Early studies indicate that it's typically well-tolerated, but more research is required to determine what the flight-and-fight agonist does over several days or weeks.
How is ARA-290 administered?
In clinical trials, it is usually injected subcutaneously. Its exact dosing and administration details will vary with future approvals, clinical guidelines, etc.
What makes ARA-290 unique?
Its activity is restricted to IRR, and unlike the traditional erythropoietin treatment it does not stimulate red blood cell production, thereby making this a safer approach for applications where erythropoiesis side effects are undesirable.
What is erythropoiesis?
Erythropoiesis is the production of red blood cells (erythrocytes). This predominantly takes place in the bone marrow and is controlled by the hormone erythropoietin which is released from the kidneys, when those senses low oxygen. The red blood cells are essential for delivering oxygen to body tissues and removing carbon dioxide; thus, erythropoiesis is an indispensable process for physiological equilibrium and organ function.
Purchase ARA-290 2 mg Pre-mixed pen from Direct Peptides. It has pre-mixed cartridge kit and pen, carry case & needle tips. Single Mixed Cartridges are sold in 1,2 and 3 options with preform needle tips; no kit included. Buy 3 cartridges & save 10%.
Examined for antiinflammatory in neurological disease.
Investigated as a therapy for peripheral neuropathic pain states.
Investigated for its ability to facilitate nerve repair and regeneration in diverse injury models.
Tested for the treatment of diabetic autonomic neuropathy.
Evaluated for its potency against spared nerve injury.
Regarded as a prospective treatment for neuroinflammation with less side effects.
Studied experimentally to determine how it works in non-erythropoietic peptides.
At Direct Peptides, we have ARA-290 peptides for sale at 99% purity. Our meticulous quality control allows us to produce small batches that meet the highest potency standards.
Our premium product is a great investment in cutting-edge treatments for nerve-related conditions and chronic pain.
When you purchase ARA-290 from us, you will receive a high-quality compound that has been formulated to produce dependable results when used for research.Trackable Shipping.
Buy ARA-290 Today From Direct Peptides, a Trusted Supplier of peptides online. We have 2mg vials, nasal sprays with either a 15ml or 30 ml bottle size and we also have in stock Blue top HGH bundles packages available for you particular research needs. Trust in Direct Peptides to supply you with the best, high purity ARA-290 available for your research directpeptides.
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DISCLAIMER: For external use only, for research purposes. They can only be used for research & development purposes, and are to be used directly in conjunction with a laboratory using S2 registration. All information on our Direct Peptides website is for educational purposes only. These are not for human or animal use or consumption. Unauthorised personnel should not be involved in processing these articles. They are not to be considered as a medicinal product, food, cosmetic or any other similar substance and are neither to be falsely labelled or used accordingly.
An in-depth analysis of the potential benefits of combining peptides into a stack to increase their individual.
This blog discusses ARA-290 as a potential therapeutic approach for RA, a chronic inflammatory autoimmune disease involving joint inflammation, pain and long-term damage. We discuss the anti-inflammatory and neuroprotective effects of the peptide, focusing on its potential to modulate inflammation, protect nerve fibres, and aid tissue repair. scription here
This blog talks about how ARA-290 acts on the Innate Repair Receptor to decrease inflammation and promote healing without interfering with red blood cell production. Research in conditions such as multiple sclerosis and diabetic retinopathy point to its potential for lessening inflammation and assisting repair. Ongoing studies are looking to establish its safety and long-term efficacy, giving hope for improved treatments of autoimmune disorders.
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